Anti-EphB3 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P54753
Gene Id	2049
Gene Symbols	EPHB3
Protein Name / Synonyms	EphB3
Clonality	Polyclonal
Preparation	This EphB3 antibody is generated from rabbits immunized with EphB3 his fusion protein.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB3, a member of the Tyr family of protein kinases, is a receptor for members of the ephrin-B family; it binds to both ephrin-B1 and -B2. Expression of this Type I membrane protein is ubiquitous. The protein contains putative domains for 2 fibronectin type III and 1 sterile alpha motif (SAM).

Specificity

Other Names

EPHB3; ETK2; HEK2; TYRO6; Ephrin type-B receptor 3; EPH-like tyrosine kinase 2; Embryonic kinase 2; Tyrosine-protein kinase TYRO6

NCBI Accession #

NP_004434.2

Other Accession #

NP_004434

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

110330

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	Western blot analysis of EphB3 Antibody (Cat# 102-17476) in C6 cell line lysates (35ug/lane).EphB3 (arrow) was detected using the purified Pab
	Western blot analysis of EphB3 Antibody (Cat# 102-17476) in mouse stomach tissue lysates (35ug/lane).EphB3 (arrow) was detected using the purified Pab.
	EphB3 Antibody (Cat# 102-17476) flow cytometric analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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