Anti-EPM2A (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O95278
Gene Id	7957
Gene Symbols	EPM2A
Protein Name / Synonyms	EPM2A (C-term)
Clonality	Polyclonal
Preparation	This EPM2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-317 amino acids from the C-terminal region of human EPM2A.
Concentration (lot specific)	2.000 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

EPM2A is a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations have been associated with myoclonic epilepsy of Lafora.

Specificity

Other Names

EPM2A; Laforin; Lafora PTPase

NCBI Accession #

NP_001018051.1;NP_005661.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

37158

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of EPM2A (arrow) using rabbit polyclonal EPM2A Antibody (C-term) (Cat# 102-12528). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EPM2A gene (Lane 2) (Origene Technologies).
	Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with EPM2A antibody (C-term) (Cat# 102-12528), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.