RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-ESR1 isoform4 (C-term) Antibody

Catalog #: 102-14368

Rabbit Anti-Human ESR1 isoform4(C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P03372
Gene Id
2099
Gene Symbols
ESR1
Protein Name / Synonyms
ESR1 isoform4(C-term)
ClonalityPolyclonal
PreparationThis ESR1 isoform4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human ESR1 isoform4.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Research AreaInflammation
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Specificity

Other Names
ESR1; ESR; NR3A1; Estrogen receptor; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
NCBI Accession #
NP_000116.2;NP_001116212.1;NP_001116213.1;NP_001116214.1
Other Accession #
NP_000116.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
66216
Recommended Dilutions
WB: 1:1000
ESR1 isoform4 Antibody (C-term) (Cat# 102-14368) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the ESR1 antibody detected the ESR1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.