Anti-ESR2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q92731
Gene Id	2100
Gene Symbols	ESR2
Protein Name / Synonyms	ESR2(C-term)
Clonality	Polyclonal
Preparation	This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human ESR2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Specificity

Predicted Reactivity

Bovine

Other Names

ESR2; ESTRB; NR3A2; Estrogen receptor beta; Nuclear receptor subfamily 3 group A member 2

NCBI Accession #

NP_001035365.1;NP_001201831.1;NP_001201832.1;NP_001258805.1;NP_001258806.1;NP_001428.1

Other Accession #

Q9XSB5; NP_001035365.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

59216

Recommended Dilutions

WB: 1:1000

ESR2 Antibody (C-term) (Cat# 102-14301) western blot analysis in MCF-7 cell line and human placenta tissue lysates (35ug/lane).This demonstrates the ESR2 antibody detected the ESR2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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