Anti-ESX1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8N693
Gene Id	80712
Gene Symbols	ESX1
Protein Name / Synonyms	ESX1 (N-term)
Clonality	Polyclonal
Preparation	This ESX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human ESX1.
Concentration (lot specific)	0.280 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis.

Specificity

Other Names

ESX1; ESX1L; ESX1R; Homeobox protein ESX1; Extraembryonic, spermatogenesis, homeobox 1; Homeobox protein ESX1-N; Homeobox protein ESX1-C

NCBI Accession #

NP_703149.1

Other Accession #

NP_703149.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

44297

Recommended Dilutions

WB: 1:1000

ESX1 Antibody (N-term) (Cat# 102-13340) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ESX1 antibody detected the ESX1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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