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Anti-ETFA (C-term) Antibody
Catalog #: 102-10956
Rabbit Anti-ETFA (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P13804 |
| Gene Id | 2108 |
| Gene Symbols | ETFA |
| Protein Name / Synonyms | ETFA (C-term) |
| Clonality | Polyclonal |
| Preparation | This ETFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human ETFA. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | IHC-P, FC, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Specificity
Predicted Reactivity
Rat, Bovine, Monkey
Other Names
ETFA; Electron transfer flavoprotein subunit alpha, mitochondrial
NCBI Accession #
NP_000117.1;NP_001121188.1
Other Accession #
P13803; Q99LC5; Q8HXY0; Q2KJE4; NP_000117.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
35080
Recommended Dilutions
IHC: 1:50-100; FC: 1:10-50; WB: 1:1000
 | ETFA Antibody (C-term) (Cat# 102-10956)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ETFA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | ETFA Antibody (C-term) (Cat# 102-10956) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
 | ETFA Antibody (C-term) (Cat# 102-10956) western blot analysis in K562 cell line and mouse liver tissue lysates (35ug/lane).This demonstrates the ETFA antibody detected the ETFA protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.