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Anti-FABP3 Antibody
Catalog #: 130-10061
Rabbit Anti-Human FABP3 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Accession Number | P05413 |
| Gene Id | 2170 |
| Gene Symbols | FABP3 FABP11 MDGI |
| Clonality | Polyclonal |
| Immunogen | Immunogen was recombinant protein derived from human FABP3. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Recommended Applications | ELISA (recommended work dilution= 1: 40, 000) |
| Antigen Catalog Number | 230-00037 |
| Reconstitution | Supplied as lyophilized and purified antibody originally containing PBS, without preservative stabilizers, such as sodium azide. Reconstitute the antibody with sterile water. The final concentration is 1 mg/ml. Avoid repeated freeze-thaw cycles. |
| Research Area | Cardiovascular Disease |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acylCoA esters. FABPs play key roles as transport vehicles of fatty compounds throughout the cytoplasm. In addition to maintain the levels of cellular membrane fatty acids, FABP family members are found to function in the modulation of cell growth and differentiation and in the modulation of specific enzymes. Human FABP3, one of the FABPs, is present in a wide variety of tissues with the highest concentrationsin cardiac and skeletal muscle. FABP3 has been used as a serological biomarker of cardiac injury.
Specificity
The antibody can specifically bind to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse and rat FABP3 has not yet been tested.
Storage
The antibody is stable for years from the data of receipt when stored at -20°C to -70°C. Reconstituted antibody (suggesting with sterile PBS) can be aliquoted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss activity. Upon reconstitution, the antibody can also be stored at 4°C for 1 month. Store at -20°C, if not intended for use within a month, keep it at 4°C and minimize freezing and thawing when use.
Related Products
Recombinant Human Fatty Acid Binding Protein 3 (cat# 230-00037) Recombinant Human Fatty Acid Binding Protein-3 (cat#228-10424)
References
- Shin HD et al.. (2003) Polymorphisms in fatty acid-binding protein-3 (FABP3) - putative association with type 2 diabetes mellitus. Hum Mutat. 22(2):180.
- Pritt ML et al.. (2008) Fabp3 as a biomarker of skeletal muscle toxicity in the rat: comparison with conventional biomarkers. Toxicol Sci. 103(2):382-96.
Expiration:
12 months from the date of shipment when stored properly.