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Anti-FABP3 Antibody, Biotinylated
Catalog #: 130-10061B-50
Rabbit anti-FABP3 Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P05413 |
| Gene Id | 2170 |
| Gene Symbols | FABP3 FABP11 MDGI |
| Clonality | Polyclonal |
| Immunogen | Immunogen was recombinant protein derived from human FABP3. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1: 40, 000) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Research Area | Cardiovascular Disease |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acylCoA esters. FABPs play key roles as transport vehicles of fatty compounds throughout the cytoplasm. In addition to maintain the levels of cellular membrane fatty acids, FABP family members are found to function in the modulation of cell growth and differentiation and in the modulation of specific enzymes. Human FABP3, one of the FABPs, is present in a wide variety of tissues with the highest concentrationsin cardiac and skeletal muscle. FABP3 has been used as a serological biomarker of cardiac injury.
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
The antibody can specifically bind to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse and rat FABP3 has not yet been tested.
Related Products
Recombinant Human Fatty Acid Binding Protein 3 (cat# 230-00037) Recombinant Human Fatty Acid Binding Protein-3 (cat#228-10424)
References
- Shin HD et al.. (2003) Polymorphisms in fatty acid-binding protein-3 (FABP3) - putative association with type 2 diabetes mellitus. Hum Mutat. 22(2):180.
- Pritt ML et al.. (2008) Fabp3 as a biomarker of skeletal muscle toxicity in the rat: comparison with conventional biomarkers. Toxicol Sci. 103(2):382-96.
Expiration:
12 months from the date of shipment when stored properly.