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Anti-FAS Antibody
Catalog #: 102-15849
Rabbit Anti-Human FAS Antibody, 100 µg
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P25445 |
| Gene Id | 355 |
| Gene Symbols | FAS |
| Protein Name / Synonyms | FAS |
| Clonality | Polyclonal |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Apoptosis, Autoimmune Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Specificity
Other Names
Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, FAS, APT1, FAS1, TNFRSF6
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
37732
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of lysate from HT-1080 cell line,using FAS Antibody(C0355). C0355 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug. |
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.