Anti-FGA (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Accession Number	P02671
Gene Id	2243
Gene Symbols	FGA
Protein Name / Synonyms	FGA (N-term)
Clonality	Monoclonal
Preparation	This FGA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 420-448 amino acids from the N-terminal region of human FGA.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq].

Specificity

Other Names

FGA; Fibrinogen alpha chain; Fibrinopeptide A

NCBI Accession #

NP_000499.1;NP_068657.1

Other Accession #

NP_000499.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

94973

Recommended Dilutions

WB: 1:100-500

FGA Antibody (N-term) (Cat# 102-10275) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the FGA(N-term) antibody detected the FGA(N-term) protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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