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Anti-FGFR1 (N-term) Antibody
Catalog #: 102-17496
Rabbit Anti-Human FGFR1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P11362 |
| Gene Id | 2260 |
| Gene Symbols | FGFR1 |
| Protein Name / Synonyms | FGFR1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This FGFR1 antibody is generated from rabbits immunized with a His fusion protein from human FGFR1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Angiogenesis, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
Specificity
Other Names
FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; Fibroblast growth factor receptor 1; Basic fibroblast growth factor receptor 1; Fms-like tyrosine kinase 2; N-sam; Proto-oncogene c-Fgr; CD_antigen=CD331; Flags: Precursor
NCBI Accession #
NP_001167534.1;NP_001167535.1;NP_001167536.1;NP_001167537.1;NP_001167538.1;NP_056934.2;NP_075593.1;NP_075594.1;NP_075598.2
Other Accession #
NP_075598
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
91868
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of FGFR1 Antibody (Cat# 102-17496) in mouse liver tissue lysates (35ug/lane). FGFR1 (arrow) was detected using the purified Pab. |
 | FGFR1 Antibody (Cat# 102-17496) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FGFR1 Antibody for immunohistochemistry. Clinical relevance has not been evaluated. |
 | FGFR1 Antibody (Cat# 102-17496) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.