Rabbit Anti-Human FGG (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P02679 |
| Gene Id | 2266 |
| Gene Symbols | FGG |
| Protein Name / Synonyms | FGG (C-term) |
| Clonality | Polyclonal |
| Preparation | This FGG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human FGG. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this protein lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.
Specificity
Other Names
FGG; Fibrinogen gamma chain
NCBI Accession #
NP_000500.2;NP_068656.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
51512
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | FGG Antibody (C-term) (Cat# 102-17278) western blot analysis in human blood plasma cell line lysates (35ug/lane).This demonstrates the FGG antibody detected the FGG protein (arrow). |
 | FGG Antibody (C-term) (RB18714) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FGG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | FGG Antibody (C-term) (Cat# 102-17278) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
