Anti-FH (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P07954
Gene Id	2271
Gene Symbols	FH
Protein Name / Synonyms	FH (N-term)
Clonality	Polyclonal
Preparation	This FH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-135 amino acids from the N-terminal region of human FH.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Specificity

Predicted Reactivity

Mouse, Rat, Pig, Monkey

Other Names

FH; Fumarate hydratase, mitochondrial

NCBI Accession #

NP_000134.2

Other Accession #

P14408; P10173; P97807; Q60HF9; NP_000134.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

54637

Recommended Dilutions

WB: 1:1000

FH Antibody (N-term) (Cat# 102-13818) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the FH Antibody detected the FH protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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