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Anti-FIBB (N-term) Antibody
Catalog #: 102-16796
Rabbit Anti-Human FIBB (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P02675 |
| Gene Id | 2244 |
| Gene Symbols | FGB |
| Protein Name / Synonyms | FIBB (N-term) |
| Clonality | Polyclonal |
| Preparation | This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human FIBB. |
| Concentration (lot specific) | 1.160 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Specificity
Other Names
FGB; Fibrinogen beta chain; Fibrinopeptide B
NCBI Accession #
NP_001171670.1;NP_005132.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55928
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of FIBB antibody (N-term) (Cat# 102-16796) in T47D cell line lysates (35ug/lane). FIBB (arrow) was detected using the purified Pab. |
 | FIBB Antibody (N-term) (Cat# 102-16796) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FIBB Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | FIBB Antibody (N-term) (Cat# 102-16796) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.