Anti-FKBP1B (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P68106
Gene Id	2281
Gene Symbols	FKBP1B
Protein Name / Synonyms	FKBP1B (N-term)
Clonality	Polyclonal
Preparation	This FKBP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human FKBP1B.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P, IF
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.

Specificity

Predicted Reactivity

Rat, Bovine, Rabbit

Other Names

FKBP1B; FKBP12.6; FKBP1L; FKBP9; OTK4; Peptidyl-prolyl cis-trans isomerase FKBP1B; 12.6 kDa FK506-binding protein; FK506-binding protein 1B; Immunophilin FKBP12.6; Rotamase; h-FKBP-12

NCBI Accession #

NP_004107.1;NP_473374.1

Other Accession #

P97534; Q8HYX6; Q9Z2I2; P68107

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

11783

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50; IF: 1:10-50

	Western blot analysis of FKBP1B antibody (N-term) (Cat# 102-17668) in 293 cell line lysates (35ug/lane). FKBP1B (arrow) was detected using the purified Pab.
	Western blot analysis of FKBP1B antibody (N-term) (Cat# 102-17668) in mouse cerebellum tissue lysates (35ug/lane). FKBP1B (arrow) was detected using the purified Pab.
	FKBP1B Antibody (N-term) (Cat# 102-17668) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP1B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	Confocal immunofluorescent analysis of FKBP1B Antibody (N-term)(Cat# 102-17668) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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