Anti-FOLR1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P15328
Gene Id	2348
Gene Symbols	FOLR1
Protein Name / Synonyms	FOLR1 (N-term)
Clonality	Polyclonal
Preparation	This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Specificity

Other Names

FOLR1; FOLR; Folate receptor alpha; Adult folate-binding protein; Folate receptor 1; Folate receptor, adult; KB cells FBP; Ovarian tumor-associated antigen MOv18

NCBI Accession #

NP_000793.1;NP_057936.1;NP_057937.1;NP_057941.1

Other Accession #

O15254; NP_000793.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

29819

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50; FC: 1:10-50

	FOLR1 antibody (N-term) (Cat# 102-10760) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FOLR1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	FOLR1 Antibody (N-term) (Cat# 102-10760) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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