Anti-FOLR2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	10-12 business days
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P14207
Gene Id	2350
Gene Symbols	FOLR2
Protein Name / Synonyms	FOLR2 (N-term)
Clonality	Polyclonal
Preparation	This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human FOLR2.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting, IHC-P, FC
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

Specificity

Other Names

FOLR2; Folate receptor beta; Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein

NCBI Accession #

NP_000794.3;NP_001107006.1;NP_001107007.1;NP_001107008.1

Other Accession #

Q05685

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

29280

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50; FC: 1:10-50

	FOLR2 Antibody (N-term) (Cat# 102-16138) IHC analysis in formalin fixed and paraffin embedded human spleen followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FOLR2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	FOLR2 Antibody (N-term) (Cat# 102-16138) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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