Anti-FOXA2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Rat
Host Species	Rabbit
Accession Number	Q9Y261
Gene Id	3170
Gene Symbols	FOXA2
Protein Name / Synonyms	FOXA2 (C-term)
Clonality	Polyclonal
Preparation	This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-407 amino acids from the C-terminal region of human FOXA2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.

Specificity

Predicted Reactivity

Mouse

Other Names

FOXA2; HNF3B; TCF3B; Hepatocyte nuclear factor 3-beta; Forkhead box protein A2; Transcription factor 3B

NCBI Accession #

NP_068556.2;NP_710141.1

Other Accession #

P35583; NP_068556.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

48306

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50; IF: 1:10-50

	FOXA2 Antibody (C-term) (Cat# 102-11362) western blot analysis in MCF-7 cell line and rat stomach tissue lysates (35ug/lane).This demonstrates the FOXA2 antibody detected the FOXA2 protein (arrow).
	FOXA2 Antibody (C-term) (Cat# 102-11362)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FOXA2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	Confocal immunofluorescent analysis of FOXA2 Antibody (C-term)(Cat# 102-11362) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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