Rabbit Anti-Human FXN (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q16595 |
| Gene Id | 2395 |
| Gene Symbols | FXN |
| Protein Name / Synonyms | FXN (Center) |
| Clonality | Polyclonal |
| Preparation | This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-102 amino acids from the Central region of human FXN. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
Specificity
Other Names
FXN; FRDA; X25; Frataxin, mitochondrial; Friedreich ataxia protein; Frataxin intermediate form; Frataxin(56-210); m56-FXN; Frataxin(78-210); d-FXN; m78-FXN; Frataxin mature form; Frataxin(81-210); m81-FXN
NCBI Accession #
NP_000135.2;NP_001155178.1;NP_852090.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23135
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
 | Western blot analysis of FXN Antibody (Center) (Cat# 102-16777) in CEM cell line lysates (35ug/lane). FXN (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with FXN antibody (Center)(Cat# 102-16777), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of FXN Antibody (Center)(Cat# 102-16777) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.