3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-FZD1 (Center) Antibody
Catalog #: 102-15124
Rabbit Anti-Human FZD1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UP38 |
| Gene Id | 8321 |
| Gene Symbols | FZD1 |
| Protein Name / Synonyms | FZD1 (Center) |
| Clonality | Polyclonal |
| Preparation | This FZD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-396 amino acids from the Central region of human FZD1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, FC, IHC-P |
| Research Area | Wnt-beta-Catenin Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Members of the 'frizzled' family are 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
FZD1; Frizzled-1; FzE1
NCBI Accession #
NP_003496.1
Other Accession #
Q08463; O70421
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
71158
Recommended Dilutions
WB: 1:1000; FC: 1:10-50; IHC: 1:10-50
 | Western blot analysis of anti-FZD1 Antibody (center) (Cat# 102-15124) in Hela cell line lysates (35ug/lane).FZD1(arrow) was detected using the purified Pab. |
 | Flow cytometric analysis of NCI-H292 cells using FZD1 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
 | Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with FZD1 antibody (Center) (Cat# 102-15124), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.