Anti-GAD2 (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human, Rat
Accession Number	Q05329
Gene Id	2572
Gene Symbols	GAD2
Protein Name / Synonyms	GAD2 (Ascites)
Clonality	Monoclonal
Preparation	This GAD2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from human GAD2.
Recommended Applications	Western Blotting
Research Area	Neuroscience
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Specificity

Predicted Reactivity

Mouse, Pig

Other Names

GAD2; GAD65; Glutamate decarboxylase 2; 65 kDa glutamic acid decarboxylase; Glutamate decarboxylase 65 kDa isoform

NCBI Accession #

NP_000809.1;NP_001127838.1

Other Accession #

Q05683; P48321; P48320; NP_000809.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

65411

Recommended Dilutions

WB: 1:100-1600

GAD2 Antibody (Cat# 102-10273) western blot analysis in rat brain tissue lysates (35ug/lane).This demonstrates the GAD2 antibody detected the GAD2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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