Anti-GATM (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P50440
Gene Id	2628
Gene Symbols	GATM
Protein Name / Synonyms	GATM(C-term)
Clonality	Polyclonal
Preparation	This GATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM.
Concentration (lot specific)	0.460 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Pig, Monkey

Other Names

GATM; AGAT; Glycine amidinotransferase, mitochondrial; L-arginine:glycine amidinotransferase; Transamidinase

NCBI Accession #

NP_001473.1

Other Accession #

P50442; P50441; Q9D964; Q4R806; Q2HJ74; NP_001473.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

48455

Recommended Dilutions

WB: 1:1000

GATM Antibody (C-term) (Cat# 102-14395) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GATM antibody detected the GATM protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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