Anti-GBE1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q04446
Gene Id	2632
Gene Symbols	GBE1
Protein Name / Synonyms	GBE1 (Center)
Clonality	Polyclonal
Preparation	This GBE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the Central region of human GBE1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).

Specificity

Other Names

GBE1; 1,4-alpha-glucan-branching enzyme; Brancher enzyme; Glycogen-branching enzyme

NCBI Accession #

NP_000149.3

Other Accession #

Q9D6Y9

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

80474

Recommended Dilutions

WB: 1:1000; IF: 1:10-50

	Western blot analysis of GBE1 Antibody (Center) (Cat# 102-18292) in HL-60 cell line lysates (35ug/lane). GBE1 (arrow) was detected using the purified Pab;
	Western blot analysis of GBE1 Antibody (Center) (Cat# 102-18292) in mouse liver tissue lysates (35ug/lane).GBE1 (arrow) was detected using the purified Pab.
	Confocal immunofluorescent analysis of GBE1 Antibody (Center)(Cat# 102-18292) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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