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Anti-GDF15 (N-term) Antibody
Catalog #: 102-11627
Rabbit Anti-Human GDF15 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q99988 |
| Gene Id | 9518 |
| Gene Symbols | GDF15 |
| Protein Name / Synonyms | GDF15 (N-term) |
| Clonality | Polyclonal |
| Preparation | This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human GDF15. |
| Concentration (lot specific) | 0.400 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
Specificity
Other Names
GDF15; MIC1; PDF; PLAB; PTGFB; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor
NCBI Accession #
NP_004855.2
Other Accession #
NP_004855.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
34140
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | GDF15 Antibody (N-term) (Cat# 102-11627) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GDF15 antibody detected the GDF15 protein (arrow). |
 | GDF15 Antibody (N-term) (Cat# 102-11627)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | GDF15 Antibody (N-term) (Cat# 102-11627) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.