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Anti-GDF5 (C-term) Antibody

Catalog #: 102-11366

Rabbit Anti-Human GDF5 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P43026
Gene Id
8200
Gene Symbols
GDF5
Protein Name / Synonyms
GDF5 (C-term)
ClonalityPolyclonal
PreparationThis GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human GDF5.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.

Specificity

Predicted Reactivity
Mouse
Other Names
GDF5; CDMP1; Growth/differentiation factor 5; Cartilage-derived morphogenetic protein 1; Radotermin
NCBI Accession #
NP_000548.1
Other Accession #
P43027; NP_000548.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55411
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
GDF5 Antibody (C-term) (Cat# 102-11366) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GDF5 antibody detected the GDF5 protein (arrow).
GDF5 Antibody (C-term) (Cat# 102-11366)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.