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Anti-GGCX (Center) Antibody

Catalog #: 102-10948

Rabbit Anti-Human GGCX (Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P38435
Gene Id
2677
Gene Symbols
GGCX
Protein Name / Synonyms
GGCX (Center)
ClonalityPolyclonal
PreparationThis GGCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-578 amino acids from the Central region of human GGCX.
Concentration (lot specific)
0.490 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Specificity

Predicted Reactivity
Rat
Other Names
GGCX; GC; Vitamin K-dependent gamma-carboxylase; Gamma-glutamyl carboxylase; Peptidyl-glutamate 4-carboxylase; Vitamin K gamma glutamyl carboxylase
NCBI Accession #
NP_000812.2;NP_001135741.1
Other Accession #
O88496; NP_000812.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
87561
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
GGCX Antibody (Center) (Cat# 102-10948) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GGCX antibody detected the GGCX protein (arrow).
GGCX Antibody (Center) (Cat# 102-10948)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GGCX Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.