Rabbit Anti-Human GIT1 (Y510) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9Y2X7 |
| Gene Id | 28964 |
| Gene Symbols | GIT1 |
| Protein Name / Synonyms | GIT1 (Y510) |
| Clonality | Polyclonal |
| Preparation | This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1. |
| Concentration (lot specific) | 0.320 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
GIT1; ARF GTPase-activating protein GIT1; Cool-associated and tyrosine-phosphorylated protein 1; G protein-coupled receptor kinase-interactor 1; GRK-interacting protein 1
NCBI Accession #
NP_001078923.1;NP_054749.2
Other Accession #
Q9Z272; Q68FF6
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
84341
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-GIT1 Antibody (Y510) (Cat# 102-17334) in mouse cerebellum tissue lysates (35ug/lane). GIT1 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GIT1 Antibody (Y510) (Cat# 102-17334), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.