This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:100

Recombinant fusion protein containing a sequence corresponding to amino acids 150-429 of human GLA (NP_000160.1).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.