Anti-GLDC (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P23378
Gene Id	2731
Gene Symbols	GLDC
Protein Name / Synonyms	GLDC (N-term)
Clonality	Polyclonal
Preparation	This GLDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GLDC.
Concentration (lot specific)	0.280 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Specificity

Other Names

GLDC; GCSP; Glycine dehydrogenase [decarboxylating], mitochondrial; Glycine cleavage system P protein; Glycine decarboxylase

NCBI Accession #

NP_000161.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

112730

Recommended Dilutions

WB: 1:1000

Western blot analysis of GLDC Antibody (N-term) (Cat# 102-18291) in mouse liver tissue lysates (35ug/lane). GLDC (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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