Anti-GMNN (Center Y111) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O75496
Gene Id	51053
Gene Symbols	GMNN
Protein Name / Synonyms	GMNN (Center Y111)
Clonality	Polyclonal
Preparation	This GMNN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human GMNN.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Specificity

Predicted Reactivity

Mouse

Other Names

GMNN; Geminin

NCBI Accession #

NP_001238918.1;NP_001238919.1;NP_001238920.1;NP_056979.1

Other Accession #

O88513

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

23565

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of GMNN Antibody (Center Y111) (Cat# 102-16440) in HepG2 cell line lysates (35ug/lane).GMNN (arrow) was detected using the purified Pab.
	GMNN Antibody (Center Y111) (Cat# 102-16440) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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