Rabbit Anti-Human GNS (Center S298) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P15586 |
| Gene Id | 2799 |
| Gene Symbols | GNS |
| Protein Name / Synonyms | GNS (Center S298) |
| Clonality | Polyclonal |
| Preparation | This GNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the Central region of human GNS. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Specificity
Other Names
GNS; N-acetylglucosamine-6-sulfatase; Glucosamine-6-sulfatase
NCBI Accession #
NP_002067.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
62082
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of GNS Antibody (Center S298) (Cat# 102-16828) in NCI-H460, Hela, 293 cell line lysates (35ug/lane). GNS (arrow) was detected using the purified Pab. |
 | GNS Antibody (Center S298) (Cat# 102-16828) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GNS Antibody (Center S298) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | GNS Antibody (Center S298) (Cat# 102-16828) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.