3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-GPHN (Center) Antibody
Catalog #: 102-18392
Rabbit Anti-GPHN (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9NQX3 |
| Gene Id | 10243 |
| Gene Symbols | GPHN |
| Protein Name / Synonyms | GPHN (Center) |
| Clonality | Polyclonal |
| Preparation | This GPHN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human GPHN. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
GPHN encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency.
Specificity
Predicted Reactivity
Rat, Chicken
Other Names
GPHN; GPH; KIAA1385; Gephyrin; Molybdopterin adenylyltransferase; Domain G; Molybdopterin molybdenumtransferase; Domain E
NCBI Accession #
NP_001019389.1;NP_065857.1
Other Accession #
Q03555; Q8BUV3; Q9PW38
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
79748
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | GPHN Antibody (Center) (Cat# 102-18392) western blot analysis in MCF-7,Hela,NCI-H460,HepG2 cell line and mouse liver tissue lysates (35ug/lane).This demonstrates the GPHN antibody detected the GPHN protein (arrow). |
 | GPHN Antibody (Center) (Cat# 102-18392) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPHN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | GPHN Antibody (Center) (Cat# 102-18392) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.