3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-GRK2 Antibody
Catalog #: 102-26483
Mouse Anti-GRK2 Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P25098 |
| Gene Id | 156 |
| Gene Symbols | GRK2 |
| Protein Name / Synonyms | ADRBK 1;ADRBK1;Adrenergic beta receptor kinase 1;Adrenergic beta receptor kinase |
| Clonality | Monoclonal |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
Other Information
Antigen Type
Recombinant Protein
Images
WB (1:500)
Western blot detection of GRK2 in Ramos and THP-1 cell lysates using GRK2 mouse mAb (1:500 diluted),with super ECL.Predicted band size:80KDa.Observed band size:80KDa.Exposure time:20S.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.