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Anti-GRP Antibody, Biotinylated
Catalog #: 130-10093B-50
Rabbit anti-GRP Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P07492 |
| Gene Id | 2922 |
| Gene Symbols | GRP |
| Clonality | Polyclonal |
| Immunogen | Immunogen was synthetic peptide derived from human GRP. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by Protein A/G affinity chromatography. |
| Immunogen Sequence | CVPLPAGGGTVLTKMYPRGNHWAVGHLM |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1: 80, 000) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
The antibody binds to human GRP, and no cross reactivity with unrelated antigens in ELISA. Cross reactivity with mouse or rat GRP was not tested.
Related Products
RayBio® Gastrin Releasing Peptide (GRP) EIA Kit for Serum, Plasma, Culture Supernatant and Cell Lysates (cat# EIA-GRP-1 )
References
- Spindel, E.R. et al. (1986) "Two prohormones for gastrin-releasing peptide are encoded by two mRNAs differing by 19 nucleotides." Proc. Natl. Acad. Sci. U.S.A. 83:19-23
- Lebacq-Verheyden A.-M. et al. (1988) "Posttranslational processing of endogenous and of baculovirus-expressed human gastrin-releasing peptide precursor."Mol. Cell. Biol. 8:3129-3135
Expiration:
12 months from the date of shipment when stored properly.