Anti-GSK3 beta (GSK3B) (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P49841\|Q9WV60\|P18266
Gene Id	2932
Gene Symbols	GSK3B
Protein Name / Synonyms	Glycogen synthase kinase-3 beta, GSK-3 beta, Serine/threonine-protein kinase GSK3B, GSK3B
Clonality	Polyclonal
Clone	RB03816
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.

Other Information

NCBI Accession #

NP_001139628.1;NP_002084.2

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

46744

Antigen Source

Human

Images

WB (1:1000)

The anti-GSK3B Pab (Cat. #102-27506) is used in Western blot to detect GSK3B in 293 cell lysate.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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