Anti-GSN (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P06396
Gene Id	2934
Gene Symbols	GSN
Protein Name / Synonyms	GSN (N-term)
Clonality	Monoclonal
Preparation	This GSN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

Specificity

Predicted Reactivity

Bovine

Other Names

GSN; Gelsolin; AGEL; Actin-depolymerizing factor; Brevin

NCBI Accession #

NP_000168.1;NP_001121134.1;NP_001121135.2;NP_001121136.1;NP_001121137.1;NP_001121138.1;NP_001121139.1;NP_001244958.1;NP_001244959.1;NP_937895.1

Other Accession #

Q3SX14; NP_000168.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

85698

Recommended Dilutions

WB: 1:100-500

GSN Antibody (N-term) (Cat# 102-10164) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GSN antibody detected the GSN protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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