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Anti-GSR (C-term) Antibody
Catalog #: 102-11370
Rabbit Anti-Human GSR (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P00390 |
| Gene Id | 2936 |
| Gene Symbols | GSR |
| Protein Name / Synonyms | GSR (C-term) |
| Clonality | Polyclonal |
| Preparation | This GSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-408 amino acids from the C-terminal region of human GSR. |
| Concentration (lot specific) | 0.330 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Specificity
Other Names
GSR; GLUR; GRD1; Glutathione reductase, mitochondrial
NCBI Accession #
NP_000628.2;NP_001182031.1;NP_001182032.1;NP_001182033.1
Other Accession #
NP_000628.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
56257
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50; FC: 1:10-50
 | GSR Antibody (C-term) (Cat# 102-11370) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GSR antibody detected the GSR protein (arrow). |
 | GSR Antibody (C-term) (Cat# 102-11370)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GSR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of GSR Antibody (C-term)(Cat# 102-11370) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
 | GSR Antibody (C-term) (Cat# 102-11370) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.