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Anti-HAND2 (C-term) Antibody
Catalog #: 102-16645
Rabbit Anti-Human HAND2 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P61296 |
| Gene Id | 9464 |
| Gene Symbols | HAND2 |
| Protein Name / Synonyms | HAND2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the C-terminal region of human HAND2. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis, Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
HAND2 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
Specificity
Predicted Reactivity
Mouse, Rat, Zebrafish
Other Names
HAND2; BHLHA26; DHAND; Heart- and neural crest derivatives-expressed protein 2; Class A basic helix-loop-helix protein 26; Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2
NCBI Accession #
NP_068808.1
Other Accession #
P61295; Q61039; P57102; NP_068808
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23666
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-HAND2 Antibody (C-term) (Cat# 102-16645) in NCI-H460 cell line lysates (35ug/lane). HAND2(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.