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Anti-Haspin GSG2 (Center) Antibody
Catalog #: 102-17780
Rabbit Anti-Human Haspin GSG2 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8TF76 |
| Gene Id | 83903 |
| Gene Symbols | GSG2 |
| Protein Name / Synonyms | Haspin GSG2 (Center) |
| Clonality | Polyclonal |
| Preparation | This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3).
Specificity
Other Names
Serine/threonine-protein kinase Haspin; Haploid germ cell-specific nuclear protein kinase; H-Haspin; Germ cell-specific gene 2 protein; GSG2
NCBI Accession #
NP_114171.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
88495
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Haspin Antibody (R330) (Cat# 102-17780) western blot analysis in Daudi,Raji cell line lysates (35ug/lane).This demonstrates the Haspin antibody detected the Haspin protein (arrow). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.