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Anti-HDAC11 (C-term) Antibody
Catalog #: 102-10951
Rabbit Anti-HDAC11 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q96DB2 |
| Gene Id | 79885 |
| Gene Symbols | HDAC11 |
| Protein Name / Synonyms | HDAC11 (C-term) |
| Clonality | Polyclonal |
| Preparation | This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-345 amino acids from the C-terminal region of human HDAC11. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
Specificity
Other Names
HDAC11; Histone deacetylase 11
NCBI Accession #
NP_001129513.1;NP_079103.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39183
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | The anti-HDAC11 Pab (Cat# 102-10951) is used in Western blot to detect HDAC11 in mouse brain tissue lysate. |
 | Purified rabbit anti-HDAC11 antibody (C-term)(Cat# 102-10951) was used in immunohistochemistry on Breast Carcinoma. |
 | Formalin-fixed and paraffin-embedded human testicle tumor tissue reacted with HDAC11 antibody (C-term)(Cat# 102-10951), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.