RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-HERC3 (N-term) Antibody

Catalog #: 102-14311

Rabbit Anti-Human HERC3(N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q15034
Gene Id
8916
Gene Symbols
HERC3
Protein Name / Synonyms
HERC3(N-term)
ClonalityPolyclonal
PreparationThis HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
Concentration (lot specific)
0.250 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).

Specificity

Other Names
HERC3; KIAA0032; Probable E3 ubiquitin-protein ligase HERC3; HECT domain and RCC1-like domain-containing protein 3
NCBI Accession #
NP_001258531.1;NP_055421.1
Other Accession #
NP_055421.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
117188
Recommended Dilutions
WB: 1:1000
HERC3 Antibody (N-term) (Cat# 102-14311) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the HERC3 antibody detected the HERC3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.