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Anti-HERV (ERVWE1) (Center) Antibody

Catalog #: 102-15084

Rabbit Anti-Human HERV (ERVWE1) (Center) Antibody, 200 µl

Product Description

Specifications

Size200 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9UQF0
Gene Id
30816
Gene Symbols
ERVW-1
Protein Name / Synonyms
HERV (ERVWE1) (Center)
ClonalityPolyclonal
PreparationThis HERV (ERVWE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human HERV (ERVWE1).
Concentration (lot specific)
1.900 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Specificity

Other Names
ERVW-1; ERVWE1; HERV-W_7q21.2 provirus ancestral Env polyprotein; Endogenous retrovirus group W member 1; Env-W; Envelope polyprotein gPr73; Enverin; HERV-7q Envelope protein; HERV-W envelope protein; Syncytin; Syncytin-1; Surface protein; gp50; Transmembrane protein; gp24
NCBI Accession #
NP_001124397.1;NP_055405.3

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
59866
Recommended Dilutions
WB: 1:1000
Western blot analysis of lysate from human brain tissue lysate, using Syncytin(ERVWE1) Antibody(Cat# 102-15084). 102-15084 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.