Anti-HIF1A (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q16665
Gene Id	3091
Gene Symbols	HIF1A
Protein Name / Synonyms	HIF1A (C-term)
Clonality	Polyclonal
Preparation	This HIF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 735-762 amino acids from the C-terminal region of human HIF1A.
Concentration (lot specific)	0.410 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Inflammation, Autophagy, Hypoxia Biology
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

Specificity

Predicted Reactivity

Bovine

Other Names

HIF1A; BHLHE78; MOP1; PASD8; Hypoxia-inducible factor 1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; Member of PAS protein 1; PAS domain-containing protein 8

NCBI Accession #

NP_001230013.1;NP_001521.1;NP_851397.1

Other Accession #

Q9XTA5; NP_001521.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

92670

Recommended Dilutions

WB: 1:1000

HIF1A Antibody (C-term) (Cat# 102-14570) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HIF1A antibody detected the HIF1A protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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