Anti-HIST1H2BO/HIST1H2BH (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P23527
Gene Id	8348
Gene Symbols	HIST1H2BO
Protein Name / Synonyms	HIST1H2BO/HIST1H2BH (N-term)
Clonality	Polyclonal
Preparation	This HIST1H2BO/HIST1H2BH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BO/HIST1H2BH.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Specificity

Predicted Reactivity

Mouse

Other Names

HIST1H2BO; H2BFH; H2BFN; Histone H2B type 1-O; Histone H2B.2; Histone H2B.n

NCBI Accession #

NP_003518.2

Other Accession #

Q5QNW6; Q64525; Q93079; NP_003518.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

13906

Recommended Dilutions

WB: 1:1000

HIST1H2BO/HIST1H2BH Antibody (N-term) (Cat# 102-11698) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the HIST1H2BO/HIST1H2BH antibody detected the HIST1H2BO/HIST1H2BH protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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