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Anti-HIV type 1 p24 Antibody
Catalog #: 130-10217
Mouse Anti-Recombinant HIV type 1 p24 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg | |||||||||
| Estimated Lead Time | 1-2 business days | |||||||||
| Species | Hepatitis B virus (HBV) | |||||||||
| Accession Number | Q9WMW5 | |||||||||
| Gene Symbols | p24 | |||||||||
| Clonality | Monoclonal | |||||||||
| Immunogen | Immunogen was recombinant protein. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography. | |||||||||
| Recommended Applications | ELISA (recommended work dilution= 1:160,000), Western Blotting (recommended work dilution= 1:1,000-5,000).
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| Antigen Catalog Number | 230-00505 | |||||||||
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. | |||||||||
| Research Area | Infectious Disease, HIV | |||||||||
| Shipping Type | Ambient temperature | |||||||||
| Storage | -20°C |
Description
Description
One of the obstacles to treatment of the human immunodeficiency virus is its high genetic variability. HIV can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in sooty mangabeys. HIV-1 viruses may be further divided into groups. The HIV-1 group M viruses predominate and are responsible for the AIDS pandemic. Group M can be further subdivided into subtypes based on genetic sequence data. Some of the subtypes are known to be more virulent or are resistant to different medications. Likewise, HIV-2 viruses are thought to be less virulent and transmissible than HIV-1 M group viruses, although HIV-2 is known to cause AIDS. HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a major group (Group M) and two or more minor groups. Each group is believed to represent an independent transmission of SIV into humans (but subtypes within a group are not). Total 39 ORFs are found in all six possible reading frames (RFs) of HIV-1 complete genome sequence.[3] But only few of them are functional.
Specificity
This antibody binds to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA.
Storage
Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -136°C. After reconstitution, it can be aliquotted and stored at 4°C for 1 month or at -20°C to -80°C in a manual defrost freezer for many months without detectable loss activity.
Expiration
12 months from the date of shipment when stored properly.