Anti-HKLK3 (C234) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P07288
Gene Id	354
Gene Symbols	KLK3
Protein Name / Synonyms	HKLK3 (C234)
Clonality	Monoclonal
Preparation	This HKLK3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from human HKLK3.
Recommended Applications	Western Blotting
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Specificity

Other Names

KLK3; APS; Prostate-specific antigen; Gamma-seminoprotein; Kallikrein-3; P-30 antigen; Semenogelase

NCBI Accession #

NP_001025218.1;NP_001025219.1;NP_001639.1

Other Accession #

NP_001025218.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

28741

Recommended Dilutions

WB: 1:500-1600

HKLK3 Antibody (C234) (Cat# 102-10320) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HKLK3 antibody detected the HKLK3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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