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Anti-HMGA2 (C-term) Antibody
Catalog #: 102-16480
Rabbit Anti-Human HMGA2 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P52926 |
| Gene Id | 8091 |
| Gene Symbols | HMGA2 |
| Protein Name / Synonyms | HMGA2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2. |
| Concentration (lot specific) | 0.39 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Angiogenesis, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specificity
Predicted Reactivity
Mouse
Other Names
HMGA2; HMGIC; High mobility group protein HMGI-C; High mobility group AT-hook protein 2
Other Accession #
P52927; NP_003475.1; NP_003474.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
11832
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | HMGA2 Antibody (C-term) (Cat# 102-16480) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HMGA2 antibody detected the HMGA2 protein (arrow). |
 | HMGA2 Antibody (C-term) (Cat# 102-16480) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.