Anti-HMGB2 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P26583
Gene Id	3148
Gene Symbols	HMGB2
Protein Name / Synonyms	HMGB2 (Center)
Clonality	Polyclonal
Preparation	This HMGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human HMGB2.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Specificity

Predicted Reactivity

Rat, Bovine, Pig

Other Names

HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2

NCBI Accession #

NP_001124160.1;NP_001124161.1;NP_002120.1

Other Accession #

P52925; P17741; P40673

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

24034

Recommended Dilutions

WB: 1:1000

HMGB2 Antibody (Center) (Cat# 102-17171) western blot analysis in HL-60,K562,H-4-II-E cell line lysates (35ug/lane).This demonstrates the HMGB2 antibody detected the HMGB2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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