Anti-HNF1B (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P35680
Gene Id	6928
Gene Symbols	HNF1B
Protein Name / Synonyms	HNF1B (C-term)
Clonality	Polyclonal
Preparation	This HNF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-529 amino acids from the C-terminal region of human HNF1B.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

HNF1B; TCF2; Hepatocyte nuclear factor 1-beta; Homeoprotein LFB3; Transcription factor 2; Variant hepatic nuclear factor 1

NCBI Accession #

NP_000449.1;NP_001159395.1

Other Accession #

P23899; P27889; NP_000449.1; NP_001159395.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

61324

Recommended Dilutions

WB: 1:1000

HNF1B Antibody (C-term) (Cat# 102-10946) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the HNF1B antibody detected the HNF1B protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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