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Anti-HNMT Antibody
Catalog #: 102-10253
Mouse Anti-Human HNMT Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P50135 |
| Gene Id | 3176 |
| Gene Symbols | HNMT |
| Protein Name / Synonyms | HNMT |
| Clonality | Monoclonal |
| Preparation | Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Specificity
Other Names
HNMT; Histamine N-methyltransferase
NCBI Accession #
NP_001019245.1;NP_001019246.1;NP_008826.1
Other Accession #
NP_008826.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
33295
Recommended Dilutions
WB: 1:100-1000
 | HNMT Antibody (Cat# 102-10253) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HNMT antibody detected the HNMT protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.